Manuel will undergo a “minor knee procedure,” the Bills said.
“He will miss the remainder of the preseason and then be re-evaluated at that time,” coach Doug Marrone said in a statement.
Veteran Kevin Kolb, who Emanuel is competing with for the quarterback position, will get the start for the team’s third preseason game next Saturday against the Washington Redskins.
Manuel came in the second half of Friday’s win over the Minnesota Vikings. The young player completed 10 of 12 passes for 92 yards and a touchdown. Emanuel was injured in the game, but the team did not announce the injury until Saturday.
Throughout two games this preseason, Manuel completed 26 of 33 passes for 199 yards and two touchdowns, and ran four times for 29 yards.
