1. Detroit, Mich. Detroit is the most segregated city in United States with a black-white dissimilarity score of 79.6. Detroit’s inner city is almost all Black, beside a little Hispanic community in the southwest called “Mexicantown.” Whites mostly stick to the suburbs like Grosse Pointe, Dearborn, and Ferndale. The map below shows the racial lines of Detroit. The red dots represent white people, blue represents Black, orange represents Hispanic, green represents Asian, and yellow is other, according to maps of 2010 Census data by Eric Fischer.